Test Comparison

The Same Age Number Can Come From Very Different Tests

Current public prices are examples checked on October 11, 2026. Different clocks are trained for different jobs, so two products can give different answers from the same person.

Test type What it measures Current public price example Retest burden Main limit
Blood DNA methylation clock Methyl tags across DNA sites, then applies one or more aging clocks. Some products also estimate pace of aging or organ-system ages. NOVOS Age: $349 one time. TruAge: $499 one time. Another sample and another full-price test. Providers commonly suggest six to twelve months. Clock choice matters. A lower score is not proof that disease risk fell or lifespan increased.
Cheek-swab DNA methylation clock Methylation in cells collected from the inside of the cheek. TallyAge: $249 for one test, or $129 per month for a membership that includes a test every six months. Easy home collection, but a membership can make the true annual cost much higher than one test. Cell mix and a proprietary method can make comparison with blood-based clocks misleading.
Standard blood-marker composite Routine measures such as glucose, inflammation, blood counts, kidney markers, and liver markers combined into an age estimate. Often bundled with ordinary lab work or a health membership. There is no single standard panel or price. Usually requires another blood draw. Fasting, illness, medicines, and lab timing can move the result. The score may reflect a temporary health change and may use a formula that was not validated for your population.
Protein or organ-age model Proteins or other large biomarker sets used to estimate the age of specific organs or systems. Usually bundled into a premium clinic or research program; many sellers do not post a standalone price. Requires the same assay and model. A changed laboratory or model breaks the comparison. Promising research does not make every commercial organ-age score clinically actionable.
Functional aging assessment Grip strength, walking speed, balance, chair rise, cardiorespiratory fitness, or a frailty score. Often included in a clinic, physical therapy, fitness, or performance assessment; ask for the standalone price. Low laboratory burden, but the same protocol and equipment matter. It measures function rather than a molecular clock. That can make it more useful for action, but it is not interchangeable with a DNA age.
Focus Testing model
What It Covers
  • An epigenetic clock from a blood or saliva sample
  • A blood-marker composite age from standard labs
  • A proteomic or organ-specific age in newer products
  • A pace-of-aging score
  • Repeat testing at six or twelve months
  • A dashboard tying the score to lifestyle advice
Typical Cost $249 to $499 for the current consumer DNA-age examples compared here; bundled clinic and protein-based programs may cost more
Evidence Level Early: clocks predict risk across populations, individual results vary between tests and between clocks, and no trial shows that treating to a clock target improves outcomes
Regulatory Status Mostly laboratory-developed or consumer wellness tests, not FDA-cleared diagnostics
Watchouts
  • No confidence range or test-retest variability reported
  • A score attributed to a product the seller also markets
  • The clock switched between baseline and follow-up
  • The result framed as a diagnosis
Questions To Ask
  • Which clock is this and what population was it trained on?
  • How much does the result move on retest with no changes?
  • Will the same clock be used at follow-up?
  • What would a five-year drop in this number mean clinically?
Sources

Current Evidence and Published Prices

Prices and program terms can change. The check date shows when each public source was reviewed.

  1. NOVOS Age product and pricing page Lists a $349 one-time blood test with biological age, pace of aging, organ ages, and telomere length. Checked 2026-10-11
  2. TruDiagnostic TruAge product and pricing page Lists a $499 blood test and the reported clock outputs. Checked 2026-10-11
  3. Tally Health single-test price Lists $249 for one cheek-swab TallyAge test. Checked 2026-10-11
  4. Tally Health membership price and retest schedule Lists $129 per month with a TallyAge test every six months. Checked 2026-10-11
  5. Physiological Reviews: Biomarkers of aging Reviews molecular and functional aging measures and notes that no standard human aging clock has emerged. Checked 2026-10-11
  6. Expert consensus on biomarkers of aging for intervention studies Identifies candidate molecular and functional measures for research while separating research use from routine diagnosis. Checked 2026-10-11
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Related Resources

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