Cellular Senescence
A state in which damaged cells stop dividing but don't die, accumulating over time and secreting inflammatory signals that affect surrounding tissue.
Cell-level aging mechanism
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Topic directory
Aging Mechanisms
The biological processes researchers use to explain why aging happens, including hallmarks, inflammation, and system-level decline.
3 profiles in this branch
Profiles
Entries in This Branch
These profiles can overlap deliberately with the editorial layer so major topics exist as explainer content and as directory records.
Mitochondrial Dysfunction
The decline in efficiency of mitochondria, the cell's energy-producing structures, with age, reducing cellular energy output and increasing oxidative byproducts.
Cell-level aging mechanism
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Chronic Inflammation (Inflammaging)
A persistent, low-grade inflammatory state that tends to rise with age, often referred to as 'inflammaging,' distinct from the acute inflammation of an injury or infection.
System-level aging mechanism
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Parallel Coverage
Related Articles, Glossary, and FAQ
This branch intentionally overlaps with the editorial and reference layers so important concepts can be found from more than one angle.
Article
The Hallmarks of Aging
A guide to the biological processes researchers believe drive aging at the cellular level, and why they matter for longevity science.
Glossary TermLongevity
The capacity to live a long, healthy life. In modern science, longevity refers not just to maximum lifespan but to the extension of healthspan, the years lived in full physical and cognitive health.
FAQLongevity Science FAQ
Answers to the most common questions about longevity science, healthspan, biological aging, and evidence-based interventions.